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    1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, 50 mg tablets; 5 mg/5 m L, 5 mg/m L solution Immediate-acting synthetic analog of hydrocortisone. Effect depends on biotransformation to prednisolone, a conversion that may be impaired in patient with liver dysfunction. Less mineralocorticoid activity than hydrocortisone, but sodium retention and potassium depletion can occur. May be used as a single agent or conjunctively with antineoplastics in cancer therapy; also used in treatment of myasthenia gravis and inflammatory conditions and as an immunosuppressant. Systemic fungal infections and known hypersensitivity; pregnancy (category C), lactation. Patients with infections; nonspecific ulcerative colitis; diverticulitis; active or latent peptic ulcer; renal insufficiency; hypertension; osteoporosis; myasthenia gravis. Prednisolone 5 mg tablet; 5 mg/5 m L, 15 mg/5 m L syrup, 0.12%, 0.125%, 1% ophthalmic suspension Acetate 25 mg/m L, 50 mg/m L injection Sodium Phosphate 5 mg/5 m L liquid; 20 mg/m L injection; 0.125%, 1% ophthalmic solution Tebuate 20 mg/m L injection Analog of hydrocortisone with 3–5 times greater potency. Mineralocorticoid properties are minimal, and potential for sodium and water retention as well as potassium loss is reduced. Principally as an antiinflammatory and immunosuppressant agent. Safety during pregnancy (category C) or lactation is not established.

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