Duloxetine was approved for the treatment of major depression in 2004. While duloxetine has demonstrated improvement in depression-related symptoms compared to placebo, comparisons of duloxetine to other antidepressant medications have been less successful. A 2012 Cochrane Review did not find greater efficacy of duloxetine compared to SSRIs and newer antidepressants. Additionally, the review found evidence that duloxetine has increased side effects and reduced tolerability compared to other antidepressants. It thus did not recommend duloxetine as a first line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. do not list duloxetine among the recommended treatment options. A review from the Annals of Internal Medicine lists duloxetine among the first line drug treatments, however, along with citalopram, escitalopram, sertraline, paroxetine, and venlafaxine. Duloxetine hydrochloride is used in MS to treat depression and neuropathic pain. It belongs to a group of medications known as selective serotonin and norepinephrine reuptake inhibitors (SSNRI). Order generic accutane Viagras Duloxetine is used to treast major depressive disorder, generalized anxiety disorder. fibromyalgia, and pain. Includes duloxetine side effects. Duloxetine hydrochloride is used in MS to treat mental depression and neuropathic pain. It belongs to a group of medications known as selective serotonin and. In addition, duloxetine is used to help relieve nerve pain peripheral neuropathy in people with diabetes or. What conditions does Duloxetine HCL treat? It is a prescription-only drug approved for the treatment of chronic musculoskeletal pain and chronic low back pain, which can be caused by conditions such as osteoarthritis. Subsequently, it was also approved for treatment of anxiety, pain caused by diabetic neuropathy, and pain caused by fibromyalgia before gaining FDA approval for chronic musculoskeletal pain in 2010. Food and Drug Administration (FDA) in 2004 for major depressive disorder. Cymbalta increases the action of serotonin and norepinephrine, which are natural neurotransmitters produced by the body. This effect of Cymbalta alleviates depression and anxiety and decrease pain signals in the brain, spinal cord, and nerves. It has also been suggested that Cymbalta could reduce inflammation or oxidative damage, but these theories have not been proven at this time. Prior to the approval of Cymbalta for musculoskeletal pain, several double-blind, placebo-controlled, randomized clinical trials confirmed that study participants taking Cymbalta had significantly greater pain reduction than participants taking a placebo. Since its approval, more recent studies have shown that Cymbalta reduces chronic musculoskeletal pain and that it is well tolerated. The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. It is written for patients and gives information about taking or using a medicine. What Duloxetine is and what it is used for Duloxetine capsules contain the active substance duloxetine. It is possible that the leaflet in your medicine pack may differ from this version because it may have been updated since your medicine was packaged. Duloxetine increases the levels of serotonin and noradrenaline in the nervous system. Below is a text only representation of the Patient Information Leaflet. Duloxetine is used in adults to treat: Duloxetine starts to work in most people with depression or anxiety within two weeks of starting treatment, but it may take 2-4 weeks before you feel better. The original can be viewed in PDF format using the link above. Tell your doctor if you do not start to feel better after this time. The text only version may be available from RNIB in large print, Braille or audio CD. Your doctor may continue to give you Duloxetine when you are feeling better to prevent your depression or anxiety from returning. For further information call RNIB Medicine Leaflet Line on 08. In people with diabetic neuropathic pain it can take some weeks before you feel better. Duloxetine hcl used for Cymbalta duloxetine hydrochloride for Depression - Multiple., Cymbalta National Multiple Sclerosis Society Clomid twin rate It is used to treat major depressive disorder, generalized anxiety disorder. The active ingredient in Cymbalta is duloxetine hydrochloride. Cymbalta Duloxetine Uses and precautions - Medical News Today. Duloxetine Oral Uses, Side Effects, Interactions, Pictures, Warnings.. Duloxetine Dr. Reddys 30 mg Gastro-Resistant Capsules, Hard - eMC. Jan 3, 2014. Duloxetine is a drug used to treat depression and urinary urge incontinence leakage of urine and it can be also be useful for certain types of. These highlights do not include all the information needed to use duloxetine delayed-release capsules safely and effectively. See full prescribing information for. Jul 15, 2018. Duloxetine learn about side effects, dosage, special precautions, and more on MedlinePlus. How should this medicine be used? Expand.