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In fact, some patients find that Viagra (sildenafil) and Levitra (vardenafil) can start to have an effect in 15 minutes. Nevertheless, each should be approached as reliably taking effect in 1 hour. Weighing the benefits and risks of Levitra versus Cialis requires some basic knowledge of each. A brief comparison of Levitra (Vardenafil) versus Cialis (Tadalafil) can be made by examining how they can be used (‘as needed’ for either or daily for Cialis), the time it takes for them to work, the length of time they continue to work, the restrictions on how they can be taken, the contraindications to their use, and the side effects each of them might cause. Though similar, ED medications have different effects and side effects. Levitra (Vardenafil) has a relatively rapid onset compared to Cialis (Tadalafil). Levitra can be effective in as little as 1 hour, while Cialis might not take effect for 2 hours, though for some patients these medicines can work more rapidly. 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Find out all you need to know about your treatment options. Both Levitra and Viagra remain effective for 4 hours, and need to be taken 30 minutes to 1 hour before sex. Viagra contains sildenafil and Levitra contains vardenafil, both of which improve the blood flow to your penis. Cialis tablets can be taken in the morning and will still be effective in the evening. Cialis daily 5mg tablets contain a low dose of the active ingredient tadalafil and they are suitable for men who have sex more than twice a week. Both are effective for 4 hours and need to be taken about one hour before sex. A recent study found, that men who have diabetes and who found that ED treatments failed to help them get an erection, experienced an improvement when using Levitra. Although further research is required, this suggests that Levitra may work better for diabetics. It also works by increasing the blood flow to your penis and contains the active ingredient avanafil. 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