Tamoxifen used for

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    Tamoxifen used for


    Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. Tell your doctor if you have ever had a blood clot in the lungs or legs, a stroke, or a heart attack. Also tell your doctor if you smoke, if you have high blood pressure or diabetes, if your ability to move around during your waking hours is limited, or if you are taking anticoagulants ('blood thinners') such as warfarin (Coumadin). If you experience any of the following symptoms during or after your treatment, call your doctor immediately: abnormal vaginal bleeding; irregular menstrual periods; changes in vaginal discharge, especially if the discharge becomes bloody, brown, or rusty; pain or pressure in the pelvis (the stomach area below the belly button); leg swelling or tenderness; chest pain; shortness of breath; coughing up blood; sudden weakness, tingling, or numbness in your face, arm, or leg, especially on one side of your body; sudden confusion; difficulty speaking or understanding; sudden difficulty seeing in one or both eyes; sudden difficulty walking; dizziness; loss of balance or coordination; or sudden severe headache. You will need to have gynecological examinations (examinations of the female organs) regularly to find early signs of cancer of the uterus. If you are thinking about taking tamoxifen to reduce the chance that you will develop breast cancer, you should talk to your doctor about the risks and benefits of this treatment. You and your doctor will decide whether the possible benefit of tamoxifen treatment is worth the risks of taking the medication. If you need to take tamoxifen to treat breast cancer, the benefits of tamoxifen outweigh the risks. Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with tamoxifen and each time you refill your prescription. It is shown to be used for treatment of estrogen-dependent breast cancer (for women, especially those who entered the menopause period) or gynecomastia of the mammary glands in men. Also, the drug can be used in the treatment of cancer of the following organs: endometrium or ovaries, as well as kidneys. And besides this, melanomas, sarcomas (affecting soft tissues) that occur when there are estrogen receptors in the tumor. The medicine can be used to eliminate prostate cancer in case of resistance of the organism to other drugs. The action of Tamoxifen is based on its properties, which allow to interfere with the activity of estrogen receptors. Tamoxifen, along with individual metabolites, fights with E2 beyond the areas of connection with cytoplasmic estrogenic conductors in the cells of the uterus and mammary glands, and in addition to the adenohypophysis and the vagina. In addition, it exerts its influence in tumors containing an increased amount of estrogenic conductors.

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    The medication has a number of uses; the doctor prescribes Tamoxifen dosage depending on the condition being treated, existing medical condition, and the period one will be on the drug as well as other medicine one is on. Tamoxifen is the generic form of the brand-name drug Soltamox, which is used to treat some types of breast cancer in men and women. Tamoxifen is prescribed to treat metastatic breast cancer, or. Tamoxifen is currently used for the treatment of both early and advanced estrogen receptor ER-positive ER+ breast cancer in pre- and post- menopausal women.

    In 2006, the large STAR clinical study concluded that raloxifene is equally effective in reducing the incidence of breast cancer, but after an average 4-year follow-up, although the difference was not statistically significant, there were 36% fewer uterine cancers and 29% fewer blood clots in women taking raloxifene than in women taking tamoxifen. Tamoxifen improves fertility in males with infertility by disinhibiting the hypothalamic-pituitary-adrenal axis (via ER antagonism) and thereby increasing the secretion of luteinizing hormone and follicle-stimulating hormone and increasing testicular testosterone production. It is taken as a preventative measure in small doses, or used at the onset of any symptoms such as nipple soreness or sensitivity. Other drugs are taken for similar purposes such as clomiphene citrate and the anti-aromatase drugs which are used in order to try to avoid the hormone-related adverse effects. Occasionally tamoxifen is used in treatment of the rare conditions of retroperitoneal fibrosis A report in September 2009 from Health and Human Services' Agency for Healthcare Research and Quality suggests that tamoxifen, raloxifene, and tibolone used to treat breast cancer significantly reduce invasive breast cancer in midlife and older women, but also increase the risk of adverse side effects. Some cases of lower-limb lymphedema have been associated with the use of tamoxifen, due to the blood clots and deep vein thrombosis (DVT) that can be caused by this medication. Resolution of the blood clots or DVT is needed before lymphedema treatment can be initiated. side effect of tamoxifen is blood clots, including deep vein thrombosis (DVT) and pulmonary embolus. In some cases, health care professionals may use the trade name Nolvadex when referring to the generic drug name tamoxifen. This medication is classified as an "anti-estrogen." (For more detail, see "How this drug works" section below). You should seek emergency help and notify your health care provider immediately if you develop sudden chest pain and shortness of breath. Notify your health care provider within 24 hours if you notice that one leg is swollen, red, painful and/or warm to touch and the other is not. A side effect of tamoxifen can be the development of uterine cancer. Women who have not had a hysterectomy should have regular pap smears and gyn examinations. Abnormal vaginal bleeding should be reported to your health care provider.

    Tamoxifen used for

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  4. Medical information for Tamoxifen including its dosage, uses, side, effects, interactions, pictures and warnings. Therapeutic indications. 'Tamoxifen' is indicated for 1. The treatment of breast cancer.

    • Tamoxifen Uses, Side Effects, Interactions, Dosage /.
    • Tamoxifen Wiki Everipedia Medical uses.
    • Tamoxifen Oral Route Proper Use - Mayo Clinic.

    Tamoxifen is used to treat breast cancer that has spread to other parts of the body metastatic breast cancer, to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients. Pediatric Use Approved labeling describing pediatric safety and efficacy information regarding tamoxifen use in patients with McCune-Albright syn-drome is available for AstraZeneca’s tamoxifen. For more detail, see "How this drug works" section below. What Tamoxifen Is Used For Tamoxifen may be given as adjuvant therapy treatment after successful surgery in women or men with lymph.

     
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